Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16727370 | 0.86 | POLB (0.53) | HSD11B1L3MBTL1ADORA2AADORA1HSD17B10 | |
| SCHEMBL9538617 | 0.85 | NAAA (0.54) | HSD11B1L3MBTL1HSD17B10KMT2ATP53 | |
| SCHEMBL19522181 | 0.84 | HSD11B1 (0.51) | HSD11B1L3MBTL1ADORA2AADORA1HSD17B10 | |
| SCHEMBL21860340 | 0.84 | HSD11B1 (0.51) | HSD11B1L3MBTL1ADORA2AADORA1HSD17B10 | |
| SCHEMBL19522182 | 0.84 | HSD11B1 (0.51) | HSD11B1L3MBTL1ADORA2AADORA1HSD17B10 | |
| Hydrochloric Acid SCHEMBL21197517 | 0.84 | L3MBTL1 (0.51) | HSD11B1L3MBTL1ADORA2AADORA1HSD17B10 | |
| Hydrochloric Acid SCHEMBL21197531 | 0.84 | NAAA (0.53) | HSD11B1L3MBTL1HSD17B10KMT2ATP53 | |
| SCHEMBL7260975 | 0.84 | NAAA (0.57) | HSD11B1L3MBTL1HSD17B10KMT2ANAAA | |
| SCHEMBL9795281 | 0.83 | TSHR (0.57) | HSD11B1KMT2ATP53LMNANAAA | |
| SCHEMBL9795287 | 0.83 | TSHR (0.57) | HSD11B1KMT2ATP53LMNANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |