SCHEMBL726313

SCHEMBL726313

O=C(O)c1ccccc1-n1ccnc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.59
CYP3A4 P08684 5/20 0.52
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
ALDH1A1 P00352 3/20 0.50
CYP1A2 P05177 3/20 0.50
CYP2D6 P10635 3/20 0.50
CYP2C19 P33261 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
CYP2C9 P11712 2/20 0.50
MAPT P10636 2/20 0.50
MAPK1 P28482 2/20 0.50
LMNA P02545 2/20 0.50
PMP22 Q01453 1/20 0.50
ALOX15 P16050 2/20 0.48
DHODH Q02127 1/20 0.48
ADH5 P11766 1/20 0.47
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9640288 0.85 IDO1 (0.50) IDO1CYP3A4MEN1KMT2AALDH1A1
SCHEMBL1239412 0.85 IDO1 (0.54) IDO1CYP3A4MEN1KMT2AALDH1A1
SCHEMBL11802077 0.85 CYP19A1 (0.56) IDO1CYP3A4MEN1KMT2AALDH1A1
SCHEMBL1132341 0.85 IDO1 (0.57) IDO1CYP3A4MEN1KMT2AALDH1A1
SCHEMBL7364258 0.85 IDO1 (0.57) IDO1CYP3A4MEN1KMT2AALDH1A1
SCHEMBL6601781 0.85 IDO1 (0.57) IDO1CYP3A4MEN1KMT2AALDH1A1
SCHEMBL7780279 0.84 IDO1 (0.49) IDO1CYP3A4MEN1KMT2AALDH1A1
SCHEMBL7980582 0.84 IDO1 (0.49) IDO1CYP3A4MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL10438238 0.83 IDO1 (0.56) IDO1CYP3A4MEN1KMT2AALDH1A1
SCHEMBL13739919 0.82 ALDH1A1 (0.53) IDO1CYP3A4MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192626-A Manufacturing process of environment-friendly plastic packaging bag 雄县双梓纸塑包装有限公司 2025-06-24 CN claimed
CN-118638420-B Nuclear grade high-temperature ceramic fireproof foaming material and preparation method thereof 烟台金润核电材料股份有限公司 2024-12-13 CN claimed
CN-118421255-B Temperature-resistant high-viscosity adhesive and preparation method thereof 山东凯恩新材料科技有限公司 2024-10-11 CN claimed
CN-118638420-A Nuclear grade high-temperature ceramic fireproof foaming material and preparation method thereof 烟台金润核电材料股份有限公司 2024-09-13 CN claimed
CN-118421255-A Temperature-resistant high-viscosity adhesive and preparation method thereof 山东凯恩新材料科技有限公司 2024-08-02 CN claimed
CN-106946789-A A kind of two-dimentional porous metals cobalt complex and its preparation method and application 哈尔滨工业大学 2017-07-14 CN claimed
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 EP disclosed
CN-120192626-A Manufacturing process of environment-friendly plastic packaging bag 雄县双梓纸塑包装有限公司 2025-06-24 CN disclosed
CN-118638420-B Nuclear grade high-temperature ceramic fireproof foaming material and preparation method thereof 烟台金润核电材料股份有限公司 2024-12-13 CN disclosed
CN-118421255-B Temperature-resistant high-viscosity adhesive and preparation method thereof 山东凯恩新材料科技有限公司 2024-10-11 CN disclosed
US-20240327410-A1 Monoacylglycerol Lipase Modulators JANSSEN PHARMACEUTICA NV (BE) 2024-10-03 US disclosed
CN-113164458-B Monoacylglycerol lipase modulators 詹森药业有限公司 2024-09-13 CN disclosed
CN-118638420-A Nuclear grade high-temperature ceramic fireproof foaming material and preparation method thereof 烟台金润核电材料股份有限公司 2024-09-13 CN disclosed
CN-1198437-A Intermediate of benzazepine derivative YAMANOUCHI PHARMA CO LTD (JP) 1998-11-11 CN disclosed
US-5710150-A ARGININE VASOPRESSIN ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1998-01-20 US disclosed
CN-1129934-A Benzazepine derivatives, pharmaceutical compositions and intermediates thereof YAMANOUCHI PHARMA CO LTD (JP) 1996-08-28 CN disclosed
EP-0716083-A1 BENZAZEPINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND INTERMEDIATE FOR THE SAME YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1996-06-12 EP disclosed
EP-0543865-A1 BENZAMIDE DERIVATIVES RHONE-POULENC RORER LIMITED (GB) 1993-06-02 EP disclosed
US-4069035-A PLANT GROWTH REGULATORS, PICRATE DYES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-01-17 US disclosed
US-4038285-A BUFFER SOLUTIONS, PICRATE DYES, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240327410-A1 Monoacylglycerol Lipase Modulators MGLL, LPL, PNLIP IDO1 1745/4885CYP3A4 1831/4885MEN1 4127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.