Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | ATM | Q13315 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589795 | 0.79 | HDAC6 (0.56) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL7688625 | 0.77 | HDAC6 (0.43) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL5001969 | 0.75 | L3MBTL1 (0.49) | KMT2AL3MBTL1HDAC6CYP1A2MAPT | |
| SCHEMBL20227025 | 0.75 | MEN1 (0.43) | NPC1RAB9AMEN1KMT2AMAOB | |
| SCHEMBL10314567 | 0.73 | HDAC6 (0.43) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL28826073 | 0.72 | L3MBTL1 (0.46) | MEN1KMT2AL3MBTL1TDP1ATM | |
| SCHEMBL9023405 | 0.72 | LTB4R (0.59) | — | |
| SCHEMBL14745052 | 0.71 | NPC1 (0.44) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL12155468 | 0.70 | KDM4E (0.53) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL1092376 | 0.70 | L3MBTL1 (0.55) | L3MBTL1TDP1ATMCYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |