SCHEMBL7263443

SCHEMBL7263443

O=P(O)(O)c1ccccc1-c1ccccc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
BCL2L1 Q07817 1/20 0.43
CYP3A4 P08684 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
PTPN5 P54829 1/20 0.41
NPC1 O15118 3/20 0.40
POLB P06746 3/20 0.40
PTK2B Q14289 2/20 0.40
CA2 P00918 2/20 0.39
CA4 P22748 2/20 0.39
CA5A P35218 2/20 0.39
RAB9A P51151 2/20 0.39
ALPG P10696 1/20 0.38
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4956835 0.89 CA2 (0.48) ALDH1A1NPC1POLBPTK2BCA2
Phosphoric Acid SCHEMBL31187365 0.84 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10BCL2L1CYP3A4
SCHEMBL811782 0.83 CYP3A4 (0.43) ALDH1A1HPGDHSD17B10BCL2L1CYP3A4
SCHEMBL6013450 0.82 HPGD (0.39) ALDH1A1HPGDHSD17B10BCL2L1CYP3A4
SCHEMBL6013454 0.82 ALDH1A1 (0.39) ALDH1A1HPGDHSD17B10BCL2L1CYP3A4
SCHEMBL1083127 0.82 ALDH1A1 (0.39) ALDH1A1HPGDHSD17B10BCL2L1CYP3A4
SCHEMBL6013441 0.82 HPGD (0.39) ALDH1A1HPGDHSD17B10BCL2L1CYP3A4
SCHEMBL6013469 0.82 ALDH1A1 (0.39) ALDH1A1HPGDHSD17B10BCL2L1CYP3A4
SCHEMBL1227487 0.81 CYP3A4 (0.52) ALDH1A1HPGDHSD17B10CYP3A4CYP1A2
SCHEMBL11350253 0.79 CYP3A4 (0.50) ALDH1A1HPGDHSD17B10CYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1309729-C Synthesis method of oxaphosphine phenanthrine fire retardant intermediate-2-(2'hydroxy phenyl) phosphenylic acid SICHUAN DONGFANG INSULATION MA (CN) 2007-04-11 CN claimed
CN-1651442-A Synthesis method of oxaphosphine phenanthrine fire retardant intermediate-2-(2'hydroxy phenyl) phosphenylic acid SICHUAN DONGFANG INSULATION MA (CN) 2005-08-10 CN claimed
EP-3495451-B1 FLAME RETARDANT COMPOSITION HUBER CORP J M (US) 2021-09-15 EP disclosed
EP-3495451-A1 FLAME RETARDANT COMPOSITION J.M. Huber Corporation (US) 2019-06-12 EP disclosed
US-10035892-B2 Flame-retardant expandable polymers SUNPOR KUNSTSTOFF GESELLSCHAFT M.B.H. (AT) 2018-07-31 US disclosed
US-20170044342-A1 FLAME-RETARDANT EXPANDABLE POLYMERS SUNPOR KUNSTSTOFF GESELLSCHAFT M.B.H. (AT) 2017-02-16 US disclosed
US-20170044342-A1 FLAME-RETARDANT EXPANDABLE POLYMERS SUNPOR KUNSTSTOFF GESELLSCHAFT M.B.H. (AT) 2017-02-16 US disclosed
EP-2537853-B1 PHOSPHORUS-ATOM-CONTAINING OLIGOMERS, PROCESS FOR PRODUCING SAME, CURABLE RESIN COMPOSITION, CURED PRODUCT THEREOF, AND PRINTED WIRING BOARD DAINIPPON INK & CHEMICALS (JP) 2014-08-27 EP disclosed
US-20140128489-A1 Flame-retardant expandable polymers SUNPOR KUNSTSTOFF GESELLSCHAFT M.B.H. (AT) 2014-05-08 US disclosed
US-20140128489-A1 Flame-retardant expandable polymers SUNPOR KUNSTSTOFF GESELLSCHAFT M.B.H. (AT) 2014-05-08 US disclosed
US-20120292582-A1 AMMONIUM SALTS OF 9,10-DIHYDRO-10-HYDROXY-9-OXA-10-PHOSPHA-PHENANTHRENE-10-ONE KREMS CHEMIE CHEMICAL SERVICES AG (AT) 2012-11-22 US disclosed
US-20120292582-A1 AMMONIUM SALTS OF 9,10-DIHYDRO-10-HYDROXY-9-OXA-10-PHOSPHA-PHENANTHRENE-10-ONE KREMS CHEMIE CHEMICAL SERVICES AG (AT) 2012-11-22 US disclosed
CN-1309729-C Synthesis method of oxaphosphine phenanthrine fire retardant intermediate-2-(2'hydroxy phenyl) phosphenylic acid SICHUAN DONGFANG INSULATION MA (CN) 2007-04-11 CN disclosed
CN-1651442-A Synthesis method of oxaphosphine phenanthrine fire retardant intermediate-2-(2'hydroxy phenyl) phosphenylic acid SICHUAN DONGFANG INSULATION MA (CN) 2005-08-10 CN disclosed
CN-1651442-A Synthesis method of oxaphosphine phenanthrine fire retardant intermediate-2-(2'hydroxy phenyl) phosphenylic acid SICHUAN DONGFANG INSULATION MA (CN) 2005-08-10 CN disclosed
US-6646064-B2 Blend containing phosphorous compound NATIONAL SCIENCE COUNCIL (TW) 2003-11-11 US disclosed
US-20020035233-A1 Preparation of flame-retardant advanced epoxy resins and cured epoxy resins NATIONAL SCIENCE COUNCIL 2002-03-21 US disclosed
US-6291626-B1 SUITABLE FOR MAKING A FIBER-REINFORCED EPOXY RESIN COMPOSITE WHICH IS USEFUL IN FABRICATION OF PRINTED CIRCUIT BOARDS; USED IN SEMICONDUCTOR ENCAPSULATION NATIONAL SCIENCE COUNCIL (TW) 2001-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10035892-B2 Flame-retardant expandable polymers PFAS, PHOSPHO1, DHODH ALDH1A1 1023/4885HPGD 264/4885HSD17B10 92/4885
US-20120292582-A1 AMMONIUM SALTS OF 9,10-DIHYDRO-10-HYDROXY-9-OXA-10-PHOSPHA-PHENANTHRENE-10-ONE DAO, NUDT1, AOC1 ALDH1A1 1511/4885HPGD 257/4885HSD17B10 695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.