Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921146 | 0.77 | DAO (0.41) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29241812 | 0.74 | CA12 (0.56) | DAOCA12CA9GRIN2DGRIN3B | |
| SCHEMBL8919065 | 0.74 | CA12 (0.56) | DAOCA12CA9GRIN2DGRIN3B | |
| SCHEMBL7264685 | 0.74 | GABRA1 (0.41) | DAOCA12CA9F11CA1 | |
| SCHEMBL8918029 | 0.73 | DAO (0.38) | DAOCA12CA9ADRB2ADRB1 | |
| SCHEMBL8919183 | 0.73 | CHEK1 (0.43) | DAOCA12CA9CA1CA7 | |
| SCHEMBL8896840 | 0.69 | CA12 (0.55) | DAOCA12CA9GRIN2DGRIN3B | |
| SCHEMBL17505173 | 0.68 | GPR84 (0.47) | ADRB2KDM4E | |
| SCHEMBL8919040 | 0.67 | PPARG (0.38) | DAOPDE3BPDE3ARXFP1KDM4E | |
| SCHEMBL8921004 | 0.67 | CA12 (0.51) | DAOCA12CA9CA1CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4710507-A | Quinolone inotropic agents | PFIZER INC. (US) | 1987-12-01 | — | — | US | disclosed |
| CN-85100796-A | The preparation method of qualone derivative | — | 1986-10-01 | — | — | CN | disclosed |
| EP-0148623-A2 | Quinolone inotropic agents | Pfizer Limited (GB) | 1985-07-17 | — | — | EP | disclosed |