Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921146 | 0.84 | DAO (0.41) | KMT2AKDM4EMEN1PTPN11ALDH1A1 | |
| SCHEMBL8918029 | 0.80 | DAO (0.38) | GSK3BKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL8920283 | 0.77 | XDH (0.47) | CHEK1METGSK3BLIMK1DYRK1A | |
| SCHEMBL8920575 | 0.75 | HSD17B2 (0.52) | KMT2AKDM4EMEN1PTPN11ALDH1A1 | |
| SCHEMBL8919040 | 0.74 | PPARG (0.38) | KMT2AKDM4EMEN1PTPN11ALDH1A1 | |
| SCHEMBL7264698 | 0.73 | DAO (0.41) | KDM4EALDH1A1MAPTSMN1; SMN2DAO | |
| SCHEMBL30159581 | 0.73 | CREBBP (0.54) | KMT2AKDM4EMEN1PTPN11ALDH1A1 | |
| SCHEMBL16881173 | 0.73 | CREBBP (0.54) | KMT2AKDM4EMEN1PTPN11ALDH1A1 | |
| SCHEMBL1144697 | 0.72 | ACACB (0.43) | KMT2AKDM4EMEN1PTPN11ALDH1A1 | |
| SCHEMBL8922937 | 0.71 | CYP3A4 (0.43) | KMT2AKDM4EMEN1PTPN11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591751-A | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0636128-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| WO-1994019339-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |