Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TACR2 | P21452 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980151 | 0.88 | MAOA (0.56) | MAOAMAOBALDH1A1SMN1; SMN2TACR2 | |
| SCHEMBL7264998 | 0.85 | CDK4 (0.60) | ALDH1A1MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL7265006 | 0.85 | CDK4 (0.60) | ALDH1A1MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL584489 | 0.85 | TACR2 (0.62) | MAOAMAOBALDH1A1SMN1; SMN2TACR2 | |
| SCHEMBL29446267 | 0.85 | TACR2 (0.62) | MAOAMAOBALDH1A1SMN1; SMN2TACR2 | |
| SCHEMBL5215156 | 0.84 | TACR2 (0.61) | MAOAMAOBALDH1A1SMN1; SMN2TACR2 | |
| SCHEMBL29377794 | 0.83 | ALDH1A1 (0.65) | MAOAMAOBALDH1A1SMN1; SMN2TACR2 | |
| SCHEMBL161066 | 0.83 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2MAPTKDM4ENPC1 | |
| SCHEMBL752160 | 0.83 | ALDH1A1 (0.65) | MAOAMAOBALDH1A1SMN1; SMN2TACR2 | |
| SCHEMBL16151250 | 0.82 | MAOA (0.50) | MAOAMAOBALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220010356-A1 | Flash and Glow 1,2-Dioxetanes | Life Technologies Corporation | 2022-01-13 | — | — | US | disclosed |
| US-20200056222-A1 | Flash and Glow 1,2-Dioxetanes | Life Technologies Corporation | 2020-02-20 | — | — | US | disclosed |
| US-10385060-B2 | Piperidine derivative and preparation method and pharmaceutical use thereof | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2019-08-20 | — | — | US | disclosed |
| US-20180298020-A1 | Piperidine Derivative and Preparation Method and Pharmaceutical Use Thereof | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) | 2018-10-18 | — | — | US | disclosed |
| US-10087191-B2 | Piperidine derivative and preparation method and pharmaceutical use thereof | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2018-10-02 | — | — | US | disclosed |
| US-20180170943-A1 | PIPERIDINE DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2018-06-21 | — | — | US | disclosed |
| EP-3312184-A1 | PIPERIDINE DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2018-04-25 | — | — | EP | disclosed |
| US-9949966-B2 | Dihydroquinolizinones for the treatment and prophylaxis of hepatitis B virus infection | HOFFMAN-LA ROCHE INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-9949966-B2 | Dihydroquinolizinones for the treatment and prophylaxis of hepatitis B virus infection | HOFFMAN-LA ROCHE INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-9949966-B2 | Dihydroquinolizinones for the treatment and prophylaxis of hepatitis B virus infection | HOFFMAN-LA ROCHE INC. (US) | 2018-04-24 | — | — | US | disclosed |
| EP-2133332-A1 | (AZA)INDOLE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | Kissei Pharmaceutical Co., Ltd. (JP) | 2009-12-16 | — | — | EP | disclosed |
| US-20090181940-A1 | Imidazopyrazine Tyrosine Kinase Inhibitors | OSI PHARMACEUTICALS, INC. | 2009-07-16 | — | — | US | disclosed |
| US-20090018369-A1 | PROCESS FOR PREPARING ERIANIN | ZHEJIANG TIANHUANG MEDICINAL PLANT PHARMACEUTICAL CO., LTD. (CN) | 2009-01-15 | — | — | US | disclosed |
| US-20090018369-A1 | PROCESS FOR PREPARING ERIANIN | ZHEJIANG TIANHUANG MEDICINAL PLANT PHARMACEUTICAL CO., LTD. (CN) | 2009-01-15 | — | — | US | disclosed |
| US-20080306028-A1 | Erianin Salts, Their Preparation Methods and Pharmaceutical Compositions Containing the Same | THE JIANG CELL BIOMEDICAL RESEARCH CO., LTD. (CN) | 2008-12-11 | — | — | US | disclosed |
| US-20080306028-A1 | Erianin Salts, Their Preparation Methods and Pharmaceutical Compositions Containing the Same | THE JIANG CELL BIOMEDICAL RESEARCH CO., LTD. (CN) | 2008-12-11 | — | — | US | disclosed |
| US-7459554-B2 | Imidazopyrazine tyrosine kinase inhibitors | OSI PHARMACEUTICALS, INC. (US) | 2008-12-02 | — | — | US | disclosed |
| US-20080227788-A9 | IMIDAZOPYRAZINE TYROSINE KINASE INHIBITORS | BECK PATRICIA A | 2008-09-18 | — | — | US | disclosed |
| EP-1916251-A1 | ERIANIN SALTS, THEIR PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Zhe Jiang Cell Biomedical Research Co., Ltd. (CN) | 2008-04-30 | — | — | EP | disclosed |
| EP-1381590-B1 | 3,4-DI-SUBSTITUTED CYCLOBUTENE-1,2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2007-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385060-B2 | Piperidine derivative and preparation method and pharmaceutical use thereof | GPER1, CYP19A1, PGR | MAOA 1483/4885MAOB 971/4885ALDH1A1 195/4885 |
| US-20080227788-A9 | IMIDAZOPYRAZINE TYROSINE KINASE INHIBITORS | IGF1R, IRS1, IGFBP1 | MAOA 1799/4885MAOB 1546/4885ALDH1A1 703/4885 |
| US-20220010356-A1 | Flash and Glow 1,2-Dioxetanes | GLO1, DDX41, GDA | MAOA 532/4885MAOB 552/4885ALDH1A1 331/4885 |
| US-10087191-B2 | Piperidine derivative and preparation method and pharmaceutical use thereof | GPER1, CYP19A1, PGR | MAOA 1483/4885MAOB 971/4885ALDH1A1 195/4885 |
| US-20080306028-A1 | Erianin Salts, Their Preparation Methods and Pharmaceutical Compositions Containing the Same | ERLIN1, ERLIN2, SLCO4C1 | MAOA 2050/4885MAOB 1006/4885ALDH1A1 2314/4885 |
| US-20200056222-A1 | Flash and Glow 1,2-Dioxetanes | GLO1, DDX41, GDA | MAOA 532/4885MAOB 552/4885ALDH1A1 331/4885 |
| US-20180170943-A1 | PIPERIDINE DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | GPER1, CYP19A1, PGR | MAOA 1483/4885MAOB 971/4885ALDH1A1 195/4885 |
| US-20180298020-A1 | Piperidine Derivative and Preparation Method and Pharmaceutical Use Thereof | GPER1, CYP19A1, PGR | MAOA 1483/4885MAOB 971/4885ALDH1A1 195/4885 |
| US-20090018369-A1 | PROCESS FOR PREPARING ERIANIN | ERLIN1, ERLIN2, EI24 | MAOA 2829/4885MAOB 3052/4885ALDH1A1 715/4885 |
| US-20090181940-A1 | Imidazopyrazine Tyrosine Kinase Inhibitors | IGF1R, IRS1, IGFBP1 | MAOA 1799/4885MAOB 1546/4885ALDH1A1 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.