Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262766 | 0.81 | MAPT (0.62) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL1593016 | 0.72 | PRKCD (0.79) | MAPTMAPK1RAB9ANPC1IKBKB | |
| SCHEMBL7270260 | 0.71 | RAB9A (0.55) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL754259 | 0.70 | MAPT (1.00) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL29633257 | 0.70 | MAPT (1.00) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL7271120 | 0.70 | RAB9A (0.58) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL28408126 | 0.69 | MAPT (0.96) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL7912631 | 0.67 | MAPT (0.80) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL5316895 | 0.67 | TDP1 (0.63) | RAB9ANPC1IKBKBABL1EGFR | |
| SCHEMBL11471935 | 0.67 | AGTR1 (0.63) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | claimed |
| US-6653311-B1 | Minimal or no effect on cycloxygenase-1 and -2 activity | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY | 2003-11-25 | — | — | US | disclosed |