Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL9871114 | 0.92 | HTR1A (0.49) | CACNA1GHTR1ADRD2PTGS2HTR2A | |
| SCHEMBL7275861 | 0.88 | MAPT (0.55) | HTR1ADRD2HTR2AALDH1A1MAPT | |
| SCHEMBL7277915 | 0.86 | CACNA1G (0.48) | CACNA1GHTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL7275953 | 0.85 | KCNH2 (0.57) | HTR1ADRD2HTR2ATRPV4USP2 | |
| Hydrochloric Acid SCHEMBL9870939 | 0.82 | HTR2A (0.53) | HTR1ADRD2HTR2AALDH1A1MAPT | |
| SCHEMBL7277460 | 0.81 | CACNA1G (0.50) | CACNA1GHTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL9872440 | 0.81 | PARP1 (0.52) | HTR1ADRD2TRPV4ALDH1A1MAPT | |
| Cadaverine Tartrate SCHEMBL9872353 | 0.81 | MAPT (0.47) | HTR1ADRD2ALDH1A1MAPTDRD3 | |
| SCHEMBL7268869 | 0.79 | SIGMAR1 (0.58) | CACNA1GHTR1AALDH1A1MAPTDRD3 | |
| Cadaverine Tartrate SCHEMBL9870596 | 0.79 | HTR1A (0.45) | CACNA1GHTR1ADRD2HTR2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409048-A2 | Aminoalkyl substituted 2-aminothiazoles and medicines containing them | BASF Aktiengesellschaft (DE) | 1991-01-23 | — | — | EP | disclosed |