Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 2/20 | 0.48 |
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SOD1 | P00441 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268941 | 0.92 | HSD17B10 (0.51) | HTR1AHTR2AADRB1HTR2BSIGMAR1 | |
| Cadaverine Tartrate SCHEMBL9872353 | 0.90 | MAPT (0.47) | HTR1ADRD2ALDH1A1 | |
| Cadaverine Tartrate SCHEMBL9870596 | 0.88 | HTR1A (0.45) | HTR1AHTR2ADRD2USP2POLB | |
| Cadaverine Tartrate SCHEMBL9872027 | 0.84 | SIGMAR1 (0.51) | HTR1AHTR2ASIGMAR1DRD2MEN1 | |
| Cadaverine Tartrate SCHEMBL9870639 | 0.84 | PARP1 (0.46) | HTR1AHTR2ADRD2USP2ALDH1A1 | |
| SCHEMBL7275861 | 0.81 | MAPT (0.55) | HTR1AHTR2AHTR2BDRD2ALDH1A1 | |
| SCHEMBL7277915 | 0.79 | CACNA1G (0.48) | HTR1AHTR2AHTR2BSIGMAR1DRD2 | |
| Cadaverine Tartrate SCHEMBL9871618 | 0.78 | DRD2 (0.44) | HTR1AHTR2ADRD2 | |
| Cadaverine Tartrate SCHEMBL9871625 | 0.78 | DRD2 (0.44) | HTR1AHTR2ADRD2 | |
| Cadaverine Tartrate SCHEMBL9871896 | 0.78 | HTR1A (0.47) | HTR1AHTR2AHTR2BSIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071864-A | Administering for high blood pressure and central nervous syst em disorders | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |