Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 7/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9870939 | 0.86 | HTR2A (0.53) | KCNH2DRD2HTR1ADRD3SIGMAR1 | |
| SCHEMBL7268941 | 0.85 | HSD17B10 (0.51) | DRD2HTR1ATRPV4DRD3SIGMAR1 | |
| SCHEMBL7268869 | 0.81 | SIGMAR1 (0.58) | KCNH2HTR1ADRD3SIGMAR1LMNA | |
| SCHEMBL7277460 | 0.81 | CACNA1G (0.50) | DRD2HTR1ADRD3SIGMAR1HTR2A | |
| SCHEMBL7270765 | 0.78 | HTR1A (0.55) | DRD2HTR1ADRD3SIGMAR1HTR2A | |
| Cadaverine Tartrate SCHEMBL9871114 | 0.78 | HTR1A (0.49) | DRD2HTR1ATRPV4SIGMAR1HTR2A | |
| SCHEMBL7268921 | 0.77 | DRD2 (0.51) | DRD2HTR1ADRD3HTR2ALMNA | |
| SCHEMBL7275861 | 0.77 | MAPT (0.55) | KCNH2DRD2HTR1ADRD3HTR2A | |
| Cadaverine Tartrate SCHEMBL9872027 | 0.76 | SIGMAR1 (0.51) | KCNH2DRD2HTR1ADRD3SIGMAR1 | |
| SCHEMBL7277915 | 0.75 | CACNA1G (0.48) | DRD2HTR1ADRD3SIGMAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409048-A2 | Aminoalkyl substituted 2-aminothiazoles and medicines containing them | BASF Aktiengesellschaft (DE) | 1991-01-23 | — | — | EP | disclosed |