Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270099 | 0.81 | KDM4E (0.40) | DRD2ABCC1MYC | |
| SCHEMBL7275969 | 0.80 | PARP1 (0.40) | DRD2 | |
| SCHEMBL7274861 | 0.80 | DRD2 (0.51) | DRD2MYC | |
| SCHEMBL7276048 | 0.80 | MYC (0.37) | DRD2MYC | |
| Hydrochloric Acid SCHEMBL7270776 | 0.79 | DRD2 (0.50) | DRD2MYC | |
| SCHEMBL7268479 | 0.77 | LMNA (0.39) | DRD2 | |
| SCHEMBL7269116 | 0.76 | ALDH1A1 (0.44) | — | |
| SCHEMBL7270697 | 0.76 | PKM (0.38) | DRD2 | |
| SCHEMBL1339887 | 0.74 | NOTUM (0.44) | DRD2HCRTR1HCRTR2MYC | |
| SCHEMBL9486104 | 0.73 | DRD2 (0.66) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407137-B1 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5185333-A | Dopamine D2 receptor blocking agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| EP-0407137-A2 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |