Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276048 | 0.84 | MYC (0.37) | DRD2MYC | |
| SCHEMBL7275969 | 0.84 | PARP1 (0.40) | DRD2ALDH1A1 | |
| SCHEMBL7274861 | 0.84 | DRD2 (0.51) | DRD2MYC | |
| Hydrochloric Acid SCHEMBL7270776 | 0.82 | DRD2 (0.50) | DRD2MYC | |
| SCHEMBL7269336 | 0.81 | MCL1 (0.39) | DRD2MYCABCC1 | |
| SCHEMBL7268479 | 0.80 | LMNA (0.39) | DRD2MEN1KMT2A | |
| SCHEMBL7270697 | 0.79 | PKM (0.38) | DRD2MEN1KMT2A | |
| SCHEMBL7269116 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL23729551 | 0.79 | L3MBTL1 (0.37) | HTR6MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16404598 | 0.78 | HTR6 (0.40) | HTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407137-B1 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0407137-A2 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |