Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.55 |
| ▸ | DRD2 | P14416 | 7/20 | 0.55 |
| ▸ | DRD3 | P35462 | 4/20 | 0.55 |
| ▸ | HTR7 | P34969 | 4/20 | 0.55 |
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL9871896 | 0.91 | HTR1A (0.47) | HTR1ADRD2DRD3HTR7DRD4 | |
| Hydrochloric Acid SCHEMBL9870939 | 0.86 | HTR2A (0.53) | HTR1ADRD2DRD3HTR7DRD4 | |
| SCHEMBL7268771 | 0.83 | POLB (0.55) | HTR1ADRD2DRD3HTR7DRD4 | |
| SCHEMBL7268921 | 0.83 | DRD2 (0.51) | HTR1ADRD2DRD3HTR7DRD4 | |
| SCHEMBL10332823 | 0.82 | DRD2 (0.58) | HTR1ADRD2DRD3HTR7DRD4 | |
| SCHEMBL7277460 | 0.82 | CACNA1G (0.50) | HTR1ADRD2DRD3HTR7DRD4 | |
| SCHEMBL7275953 | 0.78 | KCNH2 (0.57) | HTR1ADRD2DRD3SIGMAR1HTR2A | |
| SCHEMBL7277915 | 0.76 | CACNA1G (0.48) | HTR1ADRD2DRD3DRD4HRH1 | |
| SCHEMBL7275861 | 0.76 | MAPT (0.55) | HTR1ADRD2DRD3HTR7SLC6A2 | |
| Cadaverine Tartrate SCHEMBL9871086 | 0.76 | DRD2 (0.46) | HTR1ADRD2DRD3DRD4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409048-A2 | Aminoalkyl substituted 2-aminothiazoles and medicines containing them | BASF Aktiengesellschaft (DE) | 1991-01-23 | — | — | EP | disclosed |