Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 11/20 | 0.53 |
| ▸ | DRD2 | P14416 | 10/20 | 0.53 |
| ▸ | DRD3 | P35462 | 10/20 | 0.53 |
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
| ▸ | HTR7 | P34969 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR1E | P28566 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10332753 | 0.85 | DRD4 (0.53) | POLBDRD4DRD2DRD3HTR1A | |
| SCHEMBL7270765 | 0.83 | HTR1A (0.55) | POLBDRD4DRD2DRD3HTR1A | |
| SCHEMBL10332839 | 0.81 | POLB (0.59) | POLBDRD4DRD2DRD3HTR1A | |
| SCHEMBL7277915 | 0.80 | CACNA1G (0.48) | DRD4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL7275861 | 0.80 | MAPT (0.55) | DRD2DRD3HTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL9870939 | 0.78 | HTR2A (0.53) | DRD4DRD2DRD3HTR1AHTR2A | |
| SCHEMBL7268941 | 0.78 | HSD17B10 (0.51) | POLBDRD2DRD3HTR1AHTR2A | |
| SCHEMBL7268869 | 0.78 | SIGMAR1 (0.58) | DRD3HTR1AHTR7KCNH2DRD1 | |
| SCHEMBL7270512 | 0.76 | DRD2 (0.46) | DRD4DRD2DRD3HTR1AHTR2A | |
| Cadaverine Tartrate SCHEMBL9871896 | 0.76 | HTR1A (0.47) | DRD4DRD2DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409048-A2 | Aminoalkyl substituted 2-aminothiazoles and medicines containing them | BASF Aktiengesellschaft (DE) | 1991-01-23 | — | — | EP | disclosed |