Styrene

Styrene

SCHEMBL7270853

C=Cc1ccc(OCC(=O)OC(C)(C)C)cc1.C=Cc1ccccc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.49
NPC1 O15118 2/20 0.47
MEN1 O00255 1/20 0.47
RAB9A P51151 1/20 0.47
KMT2A Q03164 1/20 0.47
PPARA Q07869 3/20 0.45
MAPT P10636 4/20 0.43
LMNA P02545 2/20 0.43
POLB P06746 1/20 0.43
CYP2C9 P11712 1/20 0.43
HPGD P15428 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
PSEN1 P49768 2/20 0.42
PSEN2 P49810 2/20 0.42
APH1B Q8WW43 2/20 0.42
NCSTN Q92542 2/20 0.42
APH1A Q96BI3 2/20 0.42
PSENEN Q9NZ42 2/20 0.42
PPARG P37231 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL412718 0.94 MEN1 (0.50) PTPN1NPC1MEN1RAB9AKMT2A
SCHEMBL2470986 0.93 PPARA (0.45) PTPN1NPC1MEN1RAB9AKMT2A
4-Vinylphenol SCHEMBL3332947 0.89 MEN1 (0.47) PTPN1NPC1MEN1RAB9AKMT2A
SCHEMBL1506736 0.86 PTPN1 (0.42) PTPN1NPC1MEN1RAB9AKMT2A
SCHEMBL2448079 0.83 ALOX15 (0.57) PTPN1NPC1MEN1RAB9AKMT2A
SCHEMBL410069 0.83 PSEN1 (0.42) PTPN1NPC1MEN1RAB9AKMT2A
4-Vinylphenol SCHEMBL1506510 0.83 MEN1 (0.43) PTPN1NPC1MEN1RAB9AKMT2A
Styrene SCHEMBL27412381 0.82 ALDH1A1 (0.40) PTPN1MEN1KMT2AMAPTLMNA
SCHEMBL9626778 0.82 PTGS2 (0.46) NPC1MEN1RAB9AKMT2APPARA
SCHEMBL22000631 0.81 MAPT (0.63) PTPN1NPC1RAB9AKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6656660-B1 Resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-02 US disclosed