SCHEMBL7271950

SCHEMBL7271950

CC(Oc1ccc(C=CC=Cc2ccc(OC(=O)C(C)(C)Cc3ccc(C=CO)cc3)cc2)cc1)OC1CCCCC1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.32
PPARD Q03181 1/20 0.32
PPARA Q07869 1/20 0.32
ELANE P08246 1/20 0.31
ACACB O00763 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
TTR P02766 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NR1H4 Q96RI1 1/20 0.30
TRPM8 Q7Z2W7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3844773 0.88 ACACB (0.32) PPARGPPARDPPARAACACBLMNA
SCHEMBL3837628 0.85 PPARG (0.30) PPARGPPARDPPARA
SCHEMBL4967712 0.83 ELANE (0.34) PPARGPPARDPPARAELANEKDM4E
SCHEMBL7265039 0.79 TRPM8 (0.32) SMN1; SMN2TRPM8
SCHEMBL10138876 0.78 ELANE (0.39) PPARGPPARAELANEKDM4EMEN1
SCHEMBL3843023 0.77 APP (0.41) KDM4EMEN1TTRMAPTKMT2A
SCHEMBL7269892 0.76 ELANE (0.34) PPARGPPARDPPARAELANE
SCHEMBL4869382 0.76 CYP3A4 (0.34) PPARGPPARDPPARALMNACYP3A4
SCHEMBL5702441 0.74 STAT3 (0.31) ACACBNR1H4
SCHEMBL26015195 0.73 ALDH1A1 (0.36) ACACBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6656660-B1 Resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-02 US disclosed
EP-1024406-A1 Resist composition WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 2000-08-02 EP disclosed