SCHEMBL727248

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14516489	0.89	HTR7 (0.47)	HTR7HTR6HTR1AHTR2AALDH1A1
	SCHEMBL3814425	0.84	BCHE (0.44)	HTR7HTR6HTR1AHTR2AALDH1A1
	SCHEMBL3823319	0.83	FUCA1 (0.46)	TSHRHTR6HTR1AKMT2AALDH1A1
	SCHEMBL6773910	0.82	QPCT (0.52)	HTR7QPCTALOX15TSHRHTR6
	SCHEMBL727205	0.81	HTR2A (0.40)	HTR7TSHRHTR6HTR2AALDH1A1
	SCHEMBL14516490	0.81	TLR7 (0.41)	ALOX15ALDH1A1SMN1; SMN2KDM4EMAPT
	SCHEMBL14516480	0.81	SIGMAR1 (0.40)	HTR7HTR6KMT2AALDH1A1POLB
	SCHEMBL14516484	0.81	BCHE (0.49)	HTR7ALOX15HTR1AHTR2AKMT2A
	SCHEMBL14516479	0.81	BCHE (0.40)	HTR7HTR6HTR1AKMT2AALDH1A1
	SCHEMBL14516487	0.81	ALDH1A1 (0.38)	KMT2AALDH1A1POLBKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.