Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281748 | 1.00 | SIGMAR1 (0.40) | SIGMAR1ALDH1A1TSHRSMN1; SMN2PTGER4 | |
| SCHEMBL7281938 | 1.00 | SIGMAR1 (0.40) | SIGMAR1ALDH1A1TSHRSMN1; SMN2PTGER4 | |
| SCHEMBL7283910 | 0.99 | SIGMAR1 (0.40) | SIGMAR1ALDH1A1TSHRSMN1; SMN2PTGER4 | |
| SCHEMBL7282203 | 0.96 | SIGMAR1 (0.43) | SIGMAR1ALDH1A1TSHRSMN1; SMN2PTGER4 | |
| SCHEMBL7274398 | 0.95 | MMP2 (0.36) | SIGMAR1ALDH1A1TSHRSMN1; SMN2PTGER4 | |
| SCHEMBL7274286 | 0.91 | PTGER4 (0.39) | SIGMAR1PTGER4MAPTRXFP1PTGER3 | |
| SCHEMBL7274357 | 0.90 | SIGMAR1 (0.40) | SIGMAR1SMN1; SMN2PTGER4MAPTRXFP1 | |
| SCHEMBL7275947 | 0.89 | ALDH1A1 (0.37) | SIGMAR1ALDH1A1TSHRSMN1; SMN2PTGER4 | |
| SCHEMBL7283503 | 0.89 | MMP2 (0.38) | SIGMAR1ALDH1A1TSHRMAPTMMP2 | |
| SCHEMBL7280204 | 0.87 | SIGMAR1 (0.39) | SIGMAR1ALDH1A1TSHRSMN1; SMN2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |