Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274357 | 0.99 | SIGMAR1 (0.40) | PTGER4SIGMAR1MAPTRXFP1PTGER3 | |
| SCHEMBL7281938 | 0.91 | SIGMAR1 (0.40) | PTGER4SIGMAR1MAPTRXFP1PTGER3 | |
| SCHEMBL7281748 | 0.91 | SIGMAR1 (0.40) | PTGER4SIGMAR1MAPTRXFP1PTGER3 | |
| SCHEMBL7272947 | 0.91 | SIGMAR1 (0.40) | PTGER4SIGMAR1MAPTRXFP1PTGER3 | |
| SCHEMBL7283910 | 0.90 | SIGMAR1 (0.40) | PTGER4SIGMAR1MAPTRXFP1PTGER3 | |
| SCHEMBL7282203 | 0.87 | SIGMAR1 (0.43) | PTGER4SIGMAR1PTGER3 | |
| SCHEMBL7274398 | 0.86 | MMP2 (0.36) | PTGER4SIGMAR1MAPTRXFP1PTGER3 | |
| SCHEMBL7275947 | 0.81 | ALDH1A1 (0.37) | PTGER4SIGMAR1PTGER3 | |
| SCHEMBL7283503 | 0.80 | MMP2 (0.38) | SIGMAR1MAPTMMP2CPB2 | |
| SCHEMBL7274292 | 0.79 | MMP2 (0.41) | SIGMAR1MAPTRXFP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |