Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17861696 | 0.84 | GPR88 (0.48) | GPR88MAPTRAB9APKMALDH1A1 | |
| SCHEMBL7267685 | 0.83 | LTA4H (0.57) | GPR88MAPTRAB9APKMALDH1A1 | |
| SCHEMBL14622133 | 0.80 | LTA4H (0.57) | RAB9APKMALDH1A1LTA4HLMNA | |
| SCHEMBL14033367 | 0.80 | LTA4H (0.63) | MAPTRAB9AALDH1A1LTA4HLMNA | |
| SCHEMBL213738 | 0.79 | KCNA3 (0.64) | MAPTRAB9APKMALDH1A1KCNA3 | |
| SCHEMBL2949666 | 0.78 | FFAR1 (0.62) | GPR88MAPTRAB9APKMALDH1A1 | |
| SCHEMBL874908 | 0.77 | ACP3 (0.56) | MAPTRAB9APKMALDH1A1NPSR1 | |
| Ammonia Solution, Strong SCHEMBL3997746 | 0.77 | KCNA3 (0.61) | MAPTRAB9APKMALDH1A1KCNA3 | |
| SCHEMBL28279031 | 0.77 | KCNA3 (0.61) | MAPTRAB9APKMALDH1A1KCNA3 | |
| SCHEMBL8339774 | 0.77 | MAPT (0.52) | MAPTRAB9APKMKCNA3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935414-A | New indolylpropanols, processes for their preparation and their use, and preparations containing the compounds | BEIERSDORF AG (DE) | 1990-06-19 | — | — | US | disclosed |
| EP-0297380-A2 | Indolyl propanols, process for their preparation, their uses and preparation containing them | Beiersdorf-Lilly GmbH (DE) | 1989-01-04 | — | — | EP | disclosed |