SCHEMBL874908

SCHEMBL874908

COc1ccc(C(Cl)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.56
CA4 P22748 1/20 0.54
LTA4H P09960 2/20 0.52
ALDH1A1 P00352 4/20 0.52
TDP1 Q9NUW8 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
PBRM1 Q86U86 1/20 0.50
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
TRPA1 O75762 1/20 0.47
NR3C1 P04150 1/20 0.46
PGR P06401 1/20 0.46
NR3C2 P08235 1/20 0.46
AR P10275 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2277677 0.91 CA1 (0.58) ACP3CA4ALDH1A1TDP1L3MBTL1
SCHEMBL28806943 0.90 ALDH1A1 (0.51) ACP3CA4LTA4HALDH1A1TDP1
SCHEMBL5941221 0.82 PBRM1 (0.62) ACP3CA4LTA4HALDH1A1TDP1
SCHEMBL14205685 0.82 SLC2A1 (0.61) ACP3CA4LTA4HALDH1A1TDP1
SCHEMBL13295535 0.82 SLC2A1 (0.61) ACP3CA4LTA4HALDH1A1TDP1
SCHEMBL40557 0.82 SLC2A1 (0.61) ACP3CA4LTA4HALDH1A1TDP1
SCHEMBL8429413 0.82 PBRM1 (0.62) ACP3CA4LTA4HALDH1A1TDP1
SCHEMBL13295540 0.82 SLC2A1 (0.61) ACP3CA4LTA4HALDH1A1TDP1
SCHEMBL13295537 0.82 SLC2A1 (0.61) ACP3CA4LTA4HALDH1A1TDP1
SCHEMBL34971 0.82 SLC2A1 (0.61) ACP3CA4LTA4HALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160031962-A1 SOLID PHASE PEPTIDE SYNTHESIS OF INSULIN USING SIDE CHAIN ACHORED LYSINE CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2016-02-04 US claimed
EP-2838915-A1 SOLID PHASE PEPTIDE SYNTHESIS OF INSULIN USING SIDE CHAIN ANCHORED LYSINE Barlos, Kleomenis K. (GR) 2015-02-25 EP claimed
WO-2013156977-A1 SOLID PHASE PEPTIDE SYNTHESIS OF INSULIN USING SIDE CHAIN ANCHORED LYSINE BARLOS KLEOMENIS K (GR) 2013-10-24 WO claimed
CN-122059950-A Compounds with proteasome agonistic activity, preparation method and application thereof 浙大城市学院 2026-05-19 CN disclosed
US-12492225-B2 Melanocyte-regulating peptides IDP DISCOVERY PHARMA, S.L. (ES) 2025-12-09 US disclosed
EP-4532513-A1 CYCLIC PEPTIDES WITH ANTIBACTERIAL ACTIVITY AGAINST MULTIDRUG RESISTANT (MDR) PATHOGENS Fundación Privada Instituto De Salud Global Barcelona (ES) 2025-04-09 EP disclosed
CN-119451974-A Cyclic peptides having antibacterial activity against Multiple Drug Resistant (MDR) pathogens 巴塞罗那全球健康研究所私人基金会 2025-02-14 CN disclosed
US-20240328014-A1 AMMONIA PRODUCTION METHOD AND AMMONIA PRODUCTION APPARATUS THE UNIVERSITY OF TOKYO (JP) 2024-10-03 US disclosed
WO-2024185801-A1 AMMONIA PRODUCTION CATALYST AND METHOD FOR PRODUCING AMMONIA USING SAID CATALYST 国立大学法人 東京大学 2024-09-12 WO disclosed
US-20240294573-A1 CONSTRAINED PEPTIDES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-09-05 US disclosed
US-20240083943-A1 VEGF-REGULATING PEPTIDES IDP DISCOVERY PHARMA, S.L. (ES) 2024-03-14 US disclosed
WO-2006084338-A1 NOVEL TUBULIN POLYMERISATION INHIBITORS BIONOMICS LIMITED (AU) 2006-08-17 WO disclosed
WO-2006002470-A1 CHIRAL LIGANDS FOR ASYMMETRIC CATALYSIS MONASH UNIVERSITY (AU) 2006-01-12 WO disclosed
WO-2005070911-A1 TRANSACETALISATION PROCESS MONASH UNIVERSITY (AU) 2005-08-04 WO disclosed
EP-0931062-B1 CONJUGATES AND SPECIFIC IMMUNOASSAYS FOR THE METHADONE METABOLITE 2-ETHYLIDINE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDINE MICROGENICS CORP (US) 2004-11-17 EP disclosed
US-6140137-A METABOLITE LINKED TO POLYPEPTIDE FOR ANALYSIS AND ANTIBODY PRODUCTION; MONITORING COMPLIANCE WITH METHADONE TREATMENT MICROGENICS CORPORATION (US) 2000-10-31 US disclosed
EP-0931062-A1 CONJUGATES AND SPECIFIC IMMUNOASSAYS FOR THE METHADONE METABOLITE 2-ETHYLIDINE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDINE MICROGENICS CORPORATION (US) 1999-07-28 EP disclosed
WO-1998054133-A1 CONJUGATES AND SPECIFIC IMMUNOASSAYS FOR THE METHADONE METABOLITE 2-ETHYLIDINE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDINE MICROGENICS CORPORATION (US) 1998-12-03 WO disclosed
US-4792554-A Pyridine compounds, pharaceutical compositions, their use in allergy therapy HOECHST AKTIENGESELLSCHAFT (DE) 1988-12-20 US disclosed
EP-0224159-A1 Pyridine compounds, substituted by basic groups, process for their preparation, medicaments containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492225-B2 Melanocyte-regulating peptides MC1R, MITF, MCHR1 ACP3 1556/4885CA4 4316/4885LTA4H 3142/4885
US-20160031962-A1 SOLID PHASE PEPTIDE SYNTHESIS OF INSULIN USING SIDE CHAIN ACHORED LYSINE IAPP, INSRR, IGFBP6 ACP3 2175/4885CA4 4265/4885LTA4H 4024/4885
US-20240294573-A1 CONSTRAINED PEPTIDES IAPP, NGLY1, VIP ACP3 356/4885CA4 1486/4885LTA4H 4331/4885
US-20240083943-A1 VEGF-REGULATING PEPTIDES VEGFA, FLT4, FLT1 ACP3 2301/4885CA4 405/4885LTA4H 4132/4885
US-20240328014-A1 AMMONIA PRODUCTION METHOD AND AMMONIA PRODUCTION APPARATUS ASNS, ASS1, CPS1 ACP3 2160/4885CA4 197/4885LTA4H 3854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.