Pyromellitic Acid

Pyromellitic Acid

SCHEMBL727311

C=C(C)C(=O)OCC(CO)OC(=O)C(=C)C.O=C(O)c1cc(C(=O)O)c(C(=O)O)cc1C(=O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
PRKCA P17252 7/20 0.36
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PRKCE Q02156 1/20 0.33
PRKCQ Q04759 1/20 0.33
PRKCD Q05655 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14944 0.86 TSHR (0.57) TSHRPRKCAPRKCEPRKCQPRKCD
Methacrylic Acid SCHEMBL5826296 0.85 TSHR (0.52) TSHRPRKCAPRKCEPRKCQPRKCD
SCHEMBL4097168 0.84 TSHR (0.45) TSHRPOLBAPEX1HTTTDP1
SCHEMBL14730856 0.84 TSHR (0.45) TSHRPOLBAPEX1HTTTDP1
Ethylene Glycol SCHEMBL8134666 0.83 TSHR (0.53) TSHRPRKCAPRKCEPRKCQPRKCD
SCHEMBL372427 0.80 TSHR (0.50) TSHRPRKCAPRKCEPRKCQPRKCD
Phosphoric Acid SCHEMBL2808627 0.80 TSHR (0.50) TSHRPRKCAPRKCEPRKCQPRKCD
Pyromellitic Acid SCHEMBL15707739 0.80 TSHR (0.44) TSHRPOLBAPEX1HTTTDP1
SCHEMBL289553 0.80 TSHR (0.44) TSHRPRKCAPRKCEPRKCQPRKCD
SCHEMBL7796976 0.80 TSHR (0.53) TSHRPRKCAPRKCEPRKCQPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190290550-A1 METFORMIN-CONTAINING DENTAL MATERIALS UNIVERSITY OF MARYLAND, BALTIMORE (US) 2019-09-26 US claimed
US-10154669-B2 Improving color and release profile of resin compositions comprising silver nanoparticles THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2018-12-18 US claimed
US-20170202752-A1 PROTEIN-REPELLENT DENTAL MATERIALS AND USE THEREOF IN DENTAL APPLICATIONS UNIVERSITY OF MARYLAND, BALTIMORE (US) 2017-07-20 US claimed
EP-3171849-A1 PROTEIN-REPELLENT DENTAL MATERIALS AND USE THEREOF IN DENTAL APPLICATIONS The University of Maryland, Baltimore (US) 2017-05-31 EP claimed
US-9480260-B2 Acrylic polymers containing metallic nanoparticles THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2016-11-01 US claimed
US-20160255840-A1 IMPROVING COLOR AND RELEASE PROFILE OF RESIN COMPOSITIONS COMPRISING SILVER NANOPARTICLES THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2016-09-08 US claimed
US-20160255839-A1 IMPROVING SHELF LIFE AND COLOR PROFILE OF RESIN COMPOSITIONS WITH SILVER NANOPARTICLES THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2016-09-08 US claimed
US-20160228335-A1 RECHARGEABLE CALCIUM PHOSPHATE-CONTAINING DENTAL MATERIALS UNIVERSITY OF MARYLAND, BALTIMORE (US) 2016-08-11 US claimed
WO-2016015005-A1 PROTEIN-REPELLENT DENTAL MATERIALS AND USE THEREOF IN DENTAL APPLICATIONS UNIVERSITY OF MARYLAND, BALTIMORE (US) 2016-01-28 WO claimed
US-20150299345-A1 ANTIBACTERIAL MONOMERS, ANTIBACTERIAL RESINS AND DENTAL COMPOSITES COMPRISING THE ANTIBACTERIAL RESINS UNIVERSITY OF MARYLAND, BALTIMORE (US) 2015-10-22 US claimed
US-20140288171-A1 ACRYLIC POLYMERS CONTAINING METALLIC NANOPARTICLES THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2014-09-25 US claimed
US-8779023-B2 In situ formation of nanoparticles in resins THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-07-15 US claimed
WO-2014062347-A1 ANTIBACTERIAL MONOMERS, ANTIBACTERIAL RESINS AND DENTAL COMPOSITES COMPRISING THE ANTIBACTERIAL RESINS UNIVERSITY OF MARYLAND, BALTIMORE (US) 2014-04-24 WO claimed
EP-2588140-A2 DENTAL COMPOSITES COMPRISING NANOPARTICLES OF AMORPHOUS CALCIUM PHOSPHATE University of Maryland, Baltimore (US) 2013-05-08 EP claimed
US-20130108708-A1 DENTAL COMPOSITES COMPRISING NANOPARTICLES OF AMORPHOUS CALCIUM PHOSPHATE UNIVERSITY OF MARYLAND, BALTIMORE (US) 2013-05-02 US claimed
WO-2012003290-A2 DENTAL COMPOSITES COMPRISING NANOPARTICLES OF AMORPHOUS CALCIUM PHOSPHATE UNIVERSITY OF MARYLAND, BALTIMORE (US) 2012-01-05 WO claimed
US-20110306699-A1 IN SITU FORMATION OF NANOPARTICLES IN RESINS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-12-15 US claimed
WO-2010077985-A1 IN SITU FORMATION OF NANOPARTICLES IN RESINS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-07-08 WO claimed
WO-2006127989-A1 DENTAL RELEASING MATERIALS ADA FOUNDATION (US) 2006-11-30 WO claimed
US-20060270752-A1 Dental releasing materials ADA FOUNDATION (US) 2006-11-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160255839-A1 IMPROVING SHELF LIFE AND COLOR PROFILE OF RESIN COMPOSITIONS WITH SILVER NANOPARTICLES MPO, RNGTT, GDA TSHR 4624/4885PRKCA 1882/4885POLB 207/4885
US-20160255840-A1 IMPROVING COLOR AND RELEASE PROFILE OF RESIN COMPOSITIONS COMPRISING SILVER NANOPARTICLES CD63, GAR1, ARG1 TSHR 4265/4885PRKCA 3577/4885POLB 2058/4885
US-20140288171-A1 ACRYLIC POLYMERS CONTAINING METALLIC NANOPARTICLES CAD, PUF60, CD63 TSHR 4830/4885PRKCA 3402/4885POLB 1999/4885
US-10154669-B2 Improving color and release profile of resin compositions comprising silver nanoparticles CD63, GAR1, ARG1 TSHR 4265/4885PRKCA 3577/4885POLB 2058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.