Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.50 |
| ▸ | F10 | P00742 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | TPH1 | P17752 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7276409 | 0.85 | F10 (0.46) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7282628 | 0.84 | SLC7A5 (0.50) | ITGB3ITGA2BTPH1SLC7A5ALPI | |
| SCHEMBL288201 | 0.84 | TPH1 (0.66) | F10F2PRSS1TPH1SLC7A5 | |
| SCHEMBL1397441 | 0.84 | TPH1 (0.66) | F10F2PRSS1TPH1SLC7A5 | |
| SCHEMBL288202 | 0.84 | TPH1 (0.66) | F10F2PRSS1TPH1SLC7A5 | |
| SCHEMBL1064252 | 0.84 | TPH1 (0.66) | F10F2PRSS1TPH1SLC7A5 | |
| Hydrochloric Acid SCHEMBL5279289 | 0.82 | TPH1 (0.64) | F10F2PRSS1TPH1SLC7A5 | |
| SCHEMBL7274080 | 0.82 | ITGB3 (0.74) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL7272904 | 0.81 | TPH1 (0.50) | ITGB3ITGA2BF2PRSS1TPH1 | |
| Hydrochloric Acid SCHEMBL8575744 | 0.78 | CPN1 (0.45) | ITGB3ITGA2BF10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |