Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 5/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727352 | 0.84 | APLNR (0.49) | NTSR1APLNRPTGS2 | |
| SCHEMBL729311 | 0.84 | NTSR1 (0.73) | NTSR1OPRM1OPRD1 | |
| SCHEMBL17114560 | 0.75 | PTGS2 (0.46) | NTSR1OPRM1OPRD1APLNRPTGS2 | |
| SCHEMBL17114525 | 0.74 | MARS1 (0.51) | NTSR1OPRM1OPRD1PTGS2 | |
| SCHEMBL8589311 | 0.73 | NTSR1 (0.44) | NTSR1OPRM1OPRD1PTGS2 | |
| SCHEMBL17114648 | 0.73 | APLNR (0.56) | NTSR1OPRM1OPRD1APLNR | |
| SCHEMBL17114647 | 0.73 | APLNR (0.56) | NTSR1OPRM1OPRD1APLNR | |
| SCHEMBL727595 | 0.72 | NTSR1 (0.74) | NTSR1OPRM1OPRD1 | |
| SCHEMBL727351 | 0.71 | NTSR1 (0.75) | NTSR1OPRM1OPRD1 | |
| SCHEMBL8295919 | 0.70 | NTSR1 (0.59) | NTSR1APLNRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011156557-A2 | COMPOUNDS ACTIVE AT THE NEUROTENSIN RECEPTOR | THOMAS JAMES B (US) | 2011-12-15 | — | — | WO | disclosed |