Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884029 | 0.89 | HDAC1 (0.42) | HDAC1HDAC2HPGDHTTITGB3 | |
| SCHEMBL7272971 | 0.87 | NAMPT (0.41) | HDAC1HDAC2HPGDMEN1KMT2A | |
| SCHEMBL7284310 | 0.87 | NAMPT (0.41) | HDAC1HDAC2HPGDMEN1KMT2A | |
| SCHEMBL7272690 | 0.87 | NAMPT (0.41) | HDAC1HDAC2HPGDMEN1KMT2A | |
| SCHEMBL7274864 | 0.86 | NAMPT (0.40) | HDAC1HDAC2HPGDMEN1KMT2A | |
| SCHEMBL7274469 | 0.86 | LMNA (0.42) | HDAC1HDAC2HPGDMEN1KMT2A | |
| SCHEMBL7273173 | 0.86 | CA12 (0.42) | HDAC1HPGDMEN1KMT2AHDAC3 | |
| SCHEMBL7282847 | 0.85 | HDAC3 (0.41) | HDAC1HDAC2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7274533 | 0.84 | TSHR (0.40) | MEN1KMT2ASMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL7274136 | 0.83 | HDAC1 (0.39) | HDAC1HDAC2ITGB3ITGA2BHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |