Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273855 | 0.89 | HDAC1 (0.39) | HDAC1HDAC2HPGDHTTKDM1A | |
| SCHEMBL7281946 | 0.86 | MMP2 (0.41) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7281757 | 0.86 | MMP2 (0.41) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7272956 | 0.86 | MMP2 (0.41) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7274399 | 0.85 | MMP2 (0.42) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7283915 | 0.85 | SIGMAR1 (0.41) | — | |
| SCHEMBL7273173 | 0.85 | CA12 (0.42) | HDAC1HPGDHDAC3HDAC8HDAC6 | |
| SCHEMBL7283508 | 0.83 | HDAC3 (0.44) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7282210 | 0.82 | SIGMAR1 (0.44) | HPGDHTT | |
| SCHEMBL7272799 | 0.82 | HDAC1 (0.41) | HDAC1HDAC2HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |