Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281899 | 0.94 | CASP3 (0.43) | TDP1L3MBTL1ALDH1A1CYP1B1ALDH2 | |
| SCHEMBL7282112 | 0.90 | TDP1 (0.43) | TDP1L3MBTL1ALDH1A1CYP1B1ALDH2 | |
| SCHEMBL7283850 | 0.87 | CASP3 (0.41) | ALDH1A1CASP3MAPTAPAF1KMT2A | |
| SCHEMBL7276025 | 0.85 | RAB9A (0.47) | TDP1L3MBTL1ALDH1A1PKMMAPK1 | |
| SCHEMBL7285181 | 0.84 | TDP1 (0.45) | TDP1L3MBTL1ALDH1A1CYP1B1ALDH2 | |
| SCHEMBL7274379 | 0.83 | FAAH (0.39) | ALDH1A1KMT2AGSK3AGSK3B | |
| SCHEMBL7275478 | 0.83 | CHRNB4 (0.39) | ALDH1A1GAARAB9AKMT2AGSK3A | |
| SCHEMBL7275324 | 0.83 | CHRNB4 (0.39) | ALDH1A1GAARAB9AKMT2AGSK3A | |
| SCHEMBL7276423 | 0.81 | FAAH (0.37) | ALDH1A1TSHRRAB9AKMT2AGSK3A | |
| SCHEMBL7283442 | 0.80 | GAA (0.39) | TDP1L3MBTL1TSHRGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |