Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 5/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277598 | 0.82 | MAPT (0.40) | — | |
| SCHEMBL7268514 | 0.80 | ABCC9 (0.42) | ABCC9 | |
| SCHEMBL8090456 | 0.72 | ABCC9 (0.46) | ABCC9 | |
| SCHEMBL8085308 | 0.70 | ABCC9 (0.38) | TSHRF10OPRM1OPRK1OPRD1 | |
| SCHEMBL9375674 | 0.65 | F10 (0.39) | TSHRF10PDK2 | |
| SCHEMBL8088453 | 0.65 | F10 (0.33) | TSHRF10OPRM1OPRK1ABCC9 | |
| SCHEMBL11395028 | 0.65 | OPRM1 (0.38) | TSHROPRM1OPRK1OPRD1 | |
| SCHEMBL7277331 | 0.64 | F10 (0.40) | TSHRF10OPRM1OPRK1OPRD1 | |
| SCHEMBL9738250 | 0.63 | OPRM1 (0.36) | TSHRF10OPRM1OPRK1OPRD1 | |
| SCHEMBL10694956 | 0.62 | ABCC9 (0.41) | ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346724-A1 | Chroman derivates | MERCK PATENT GmbH (DE) | 1989-12-20 | — | — | EP | disclosed |