Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274170 | 0.82 | TSHR (0.35) | — | |
| SCHEMBL7268514 | 0.79 | ABCC9 (0.42) | LMNAKDM4E | |
| SCHEMBL7269269 | 0.66 | MAPT (0.39) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL17456222 | 0.62 | MAPT (0.50) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL28344554 | 0.60 | CA2 (0.51) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL2267166 | 0.60 | LMNA (0.48) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL11002262 | 0.59 | MAPT (0.48) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL9140641 | 0.59 | ABCC9 (0.46) | — | |
| SCHEMBL14240450 | 0.59 | RARB (0.50) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL28813189 | 0.58 | LMNA (0.42) | MAPTALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346724-A1 | Chroman derivates | MERCK PATENT GmbH (DE) | 1989-12-20 | — | — | EP | disclosed |