Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.40 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280021 | 0.89 | FAAH (0.42) | FAAHMGLLGSK3AGSK3B | |
| SCHEMBL7275324 | 0.88 | CHRNB4 (0.39) | FAAHMGLLPYGLGSK3AGSK3B | |
| SCHEMBL7275478 | 0.88 | CHRNB4 (0.39) | FAAHMGLLPYGLGSK3AGSK3B | |
| SCHEMBL7283442 | 0.85 | GAA (0.39) | FAAHMGLLGSK3AGSK3BMEN1 | |
| SCHEMBL7282112 | 0.84 | TDP1 (0.43) | FAAHGSK3AGSK3BMAPTKMT2A | |
| SCHEMBL7276102 | 0.82 | FAAH (0.38) | FAAHMGLLGSK3AGSK3B | |
| SCHEMBL7274062 | 0.81 | ALDH1A1 (0.39) | MEN1LMNAKMT2A | |
| SCHEMBL7274075 | 0.81 | MAPT (0.48) | MAPT | |
| SCHEMBL7276128 | 0.79 | LTA4H (0.46) | MGLLMEN1KMT2A | |
| SCHEMBL7274188 | 0.78 | OGA (0.41) | FAAHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |