Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336889 | 0.91 | SIGMAR1 (0.37) | SIGMAR1ITGB3ITGA2BDRD2GLS | |
| SCHEMBL8881851 | 0.91 | SIGMAR1 (0.38) | SIGMAR1TBXA2RDRD2LTA4HGLS | |
| SCHEMBL7284329 | 0.89 | ACACB (0.41) | SIGMAR1ITGB3ITGA2BACACBACACA | |
| SCHEMBL7276603 | 0.87 | TBXA2R (0.35) | ITGB3ITGA2BTBXA2RLTA4HMTNR1A | |
| SCHEMBL7274430 | 0.85 | MTNR1A (0.35) | ITGB3ITGA2BTBXA2RLTA4HMTNR1A | |
| SCHEMBL7274101 | 0.84 | ITGB3 (0.41) | SIGMAR1ITGB3ITGA2BACACBACACA | |
| SCHEMBL7283478 | 0.82 | SIGMAR1 (0.54) | SIGMAR1 | |
| SCHEMBL7272740 | 0.82 | SIGMAR1 (0.37) | SIGMAR1DRD2GLSMTNR1ANAMPT | |
| SCHEMBL7274726 | 0.82 | SIGMAR1 (0.51) | SIGMAR1NAMPT | |
| SCHEMBL7284272 | 0.81 | ITGB3 (0.37) | SIGMAR1ITGB3ITGA2BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |