Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 4/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274430 | 0.89 | MTNR1A (0.35) | ITGB3ITGA2BMTNR1AALDH1A1TSHR | |
| Water SCHEMBL7273109 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7276603 | 0.88 | TBXA2R (0.35) | ITGB3ITGA2BMTNR1AALDH1A1TSHR | |
| SCHEMBL7336889 | 0.87 | SIGMAR1 (0.37) | ITGB3ITGA2BMTNR1ASIGMAR1 | |
| SCHEMBL7276521 | 0.84 | PNMT (0.38) | ITGB3ITGA2BSMN1; SMN2 | |
| Water SCHEMBL7275052 | 0.82 | ITGB3 (0.38) | ITGB3ITGA2BMTNR1AITGAV | |
| SCHEMBL7274241 | 0.81 | SIGMAR1 (0.39) | ITGB3ITGA2BMTNR1ASIGMAR1 | |
| SCHEMBL7276721 | 0.79 | TRPV1 (0.43) | ALDH1A1SMN1; SMN2F2ITGB1ITGA5 | |
| SCHEMBL7274533 | 0.79 | TSHR (0.40) | ITGB3ITGA2BMTNR1AALDH1A1TSHR | |
| Water SCHEMBL7283102 | 0.79 | ITGB3 (0.41) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |