Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276565 | 0.89 | HRH1 (0.43) | LTA4HALDH1A1LMNAMAPTNAMPT | |
| SCHEMBL7281268 | 0.88 | ABCB1 (0.44) | LTA4HALDH1A1LMNAMAPTHTR1A | |
| SCHEMBL7274151 | 0.88 | ABCB1 (0.44) | LTA4HALDH1A1LMNAMAPTHTR1A | |
| SCHEMBL7282551 | 0.88 | ABCB1 (0.44) | LTA4HALDH1A1LMNAMAPTHTR1A | |
| Hydrochloric Acid SCHEMBL7276269 | 0.87 | ITGB3 (0.35) | PPARGALDH1A1LMNAMAPTS1PR1 | |
| SCHEMBL7274458 | 0.86 | ABCB1 (0.43) | LTA4HALDH1A1LMNAMAPTNAMPT | |
| SCHEMBL7276554 | 0.85 | VNN1 (0.41) | PPARGLTA4HALDH1A1LMNAMAPT | |
| SCHEMBL7272626 | 0.85 | MAPT (0.36) | LTA4HALDH1A1LMNAMAPTNAMPT | |
| SCHEMBL7284386 | 0.84 | ALDH1A1 (0.36) | LTA4HALDH1A1LMNAMAPTNAMPT | |
| SCHEMBL7271733 | 0.83 | AR (0.49) | ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |