Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 8/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7275878 | 0.88 | OPRM1 (0.37) | LTA4HALDH1A1LMNAMAPTPPARG | |
| SCHEMBL7284386 | 0.88 | ALDH1A1 (0.36) | VNN1LTA4HALDH1A1LMNAMAPT | |
| SCHEMBL7272626 | 0.87 | MAPT (0.36) | LTA4HALDH1A1LMNAMAPTFFAR4 | |
| SCHEMBL7281268 | 0.87 | ABCB1 (0.44) | LTA4HALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL7282551 | 0.87 | ABCB1 (0.44) | LTA4HALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL7274151 | 0.87 | ABCB1 (0.44) | LTA4HALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL7284718 | 0.86 | HTR1A (0.42) | — | |
| SCHEMBL7274335 | 0.85 | PPARG (0.38) | LTA4HALDH1A1LMNAMAPTPPARG | |
| SCHEMBL7284876 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTNR1H4KDM4E | |
| SCHEMBL7276565 | 0.85 | HRH1 (0.43) | LTA4HALDH1A1LMNAMAPTFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |