Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | YAP1 | P46937 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281268 | 0.91 | ABCB1 (0.44) | HRH1HRH2ALDH1A1LMNAMAPT | |
| SCHEMBL7274151 | 0.91 | ABCB1 (0.44) | HRH1HRH2ALDH1A1LMNAMAPT | |
| SCHEMBL7282551 | 0.91 | ABCB1 (0.44) | HRH1HRH2ALDH1A1LMNAMAPT | |
| SCHEMBL7274335 | 0.89 | PPARG (0.38) | HRH1ALDH1A1LMNAMAPTNAMPT | |
| SCHEMBL7274458 | 0.88 | ABCB1 (0.43) | HRH1ALDH1A1LMNAMAPTABCB1 | |
| Hydrochloric Acid SCHEMBL7282181 | 0.87 | ITGB3 (0.36) | ALDH1A1LMNAMAPTFFAR4LTA4H | |
| SCHEMBL7275123 | 0.86 | AR (0.36) | HRH1ALDH1A1LMNAMAPTABCB1 | |
| SCHEMBL7273850 | 0.85 | ABCB1 (0.46) | ALDH1A1LMNAMAPTABCB1HPGD | |
| SCHEMBL7274990 | 0.85 | LTA4H (0.40) | HRH1HRH2ALDH1A1LMNAMAPT | |
| SCHEMBL7276554 | 0.85 | VNN1 (0.41) | ALDH1A1LMNAMAPTFFAR4LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |