Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7283551 | 0.89 | OPRM1 (0.39) | OPRM1KCNH2SIGMAR1 | |
| SCHEMBL7276097 | 0.89 | OGA (0.43) | — | |
| SCHEMBL7275008 | 0.88 | — | — | |
| SCHEMBL7273681 | 0.88 | ALDH1A1 (0.44) | OPRM1KCNH2SIGMAR1POLB | |
| Hydrochloric Acid SCHEMBL7282118 | 0.88 | — | — | |
| SCHEMBL7283319 | 0.87 | GAA (0.42) | — | |
| SCHEMBL7282862 | 0.85 | ALDH1A1 (0.38) | OPRM1KCNH2SIGMAR1 | |
| SCHEMBL7284041 | 0.83 | ALDH1A1 (0.42) | OPRM1KCNH2SIGMAR1 | |
| SCHEMBL7283976 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7274683 | 0.82 | SIGMAR1 (0.41) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |