SCHEMBL7276097

SCHEMBL7276097

COC(=O)C[C@@H]1C[C@@H](CO)N(CCCc2ccccc2)C1=O

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
OGA O60502 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7283319 0.91 GAA (0.42)
SCHEMBL7274559 0.89 OPRM1 (0.39)
Hydrochloric Acid SCHEMBL7283551 0.89 OPRM1 (0.39)
SCHEMBL7274188 0.88 OGA (0.41) OGA
SCHEMBL7275008 0.88
Hydrochloric Acid SCHEMBL7282118 0.87
SCHEMBL7276105 0.86 FAAH (0.40) OGA
SCHEMBL7282862 0.86 ALDH1A1 (0.38)
SCHEMBL7283976 0.84
SCHEMBL7284041 0.83 ALDH1A1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0483667-B1 Cyclic imino derivatives, process for their preparation and drugs containing them THOMAE GMBH DR K (DE) 1998-02-04 EP disclosed
US-5591769-A PYRROLIDINE DERIVATIVES; ANTICOAGULANTS KARL THOMAE GMBH (DE) 1997-01-07 US disclosed
US-5541343-A ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS KARL THOMAE GMBH (DE) 1996-07-30 US disclosed
EP-0483667-A2 Cyclic imino derivatives, process for their preparation and drugs containing them Dr. Karl Thomae GmbH (DE) 1992-05-06 EP disclosed