Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646603 | 0.85 | CTSS (0.42) | REN | |
| SCHEMBL7274687 | 0.83 | REN (0.52) | REN | |
| SCHEMBL7274926 | 0.82 | CTSK (0.47) | REN | |
| SCHEMBL7329655 | 0.79 | REN (0.67) | REN | |
| SCHEMBL9646165 | 0.78 | CTSK (0.45) | REN | |
| SCHEMBL7276220 | 0.77 | REN (0.42) | REN | |
| SCHEMBL7276223 | 0.77 | REN (0.42) | REN | |
| SCHEMBL10716186 | 0.76 | CTSK (0.48) | REN | |
| SCHEMBL10717386 | 0.76 | REN (0.53) | REN | |
| SCHEMBL9646344 | 0.76 | CTSS (0.43) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | disclosed |