Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065711 | 0.83 | ALDH1A1 (0.50) | CTSBCTSLCTSSCTSKABCB1 | |
| SCHEMBL7275440 | 0.82 | SLC15A1 (0.47) | CTSBABCB1ALDH1A1HSD17B10 | |
| SCHEMBL28721530 | 0.80 | ABCB1 (0.45) | CTSBCTSLCTSSCTSKABCB1 | |
| SCHEMBL28721531 | 0.80 | ABCB1 (0.45) | CTSBCTSLCTSSCTSKABCB1 | |
| SCHEMBL30953186 | 0.79 | ITGB3 (0.42) | CTSL | |
| SCHEMBL8111386 | 0.77 | ALDH1A1 (0.47) | CTSKABCB1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7420644 | 0.77 | ANPEP (0.43) | CTSBCTSLCTSSCTSKCAPN1 | |
| SCHEMBL7410587 | 0.75 | L3MBTL1 (0.43) | ALDH1A1HSD17B10 | |
| SCHEMBL28418276 | 0.74 | ALDH1A1 (0.47) | CTSBABCB1ALDH1A1THRBCYP2C9 | |
| SCHEMBL28418277 | 0.74 | ALDH1A1 (0.47) | CTSBABCB1ALDH1A1THRBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |
| EP-0845002-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5677282-A | ENZYME INHIBITOR; OSTEOARTHRITIS AND RHEUMATIC DISORDERS | PROSCRIPT, INC. (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1996040745-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1996-12-19 | — | — | WO | disclosed |