Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 14/20 | 0.49 |
| ▸ | PYGM | P11217 | 14/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275577 | 0.85 | CYP2C9 (0.55) | CYP2C9KDM4EMEN1CYP1A2CYP3A4 | |
| SCHEMBL10653191 | 0.83 | PYGL (0.53) | PYGLPYGMCYP2C9KDM4EMEN1 | |
| SCHEMBL7429254 | 0.80 | CYP2C9 (0.64) | PYGLPYGMCYP2C9KDM4EMEN1 | |
| SCHEMBL9770221 | 0.79 | PYGM (0.52) | PYGLPYGMCYP2C9KDM4EMEN1 | |
| SCHEMBL8199258 | 0.78 | TSHR (0.73) | CYP2C9KDM4EMEN1CYP1A2CYP3A4 | |
| SCHEMBL7408943 | 0.78 | CYP2C9 (0.73) | CYP2C9KDM4EMEN1CYP1A2CYP3A4 | |
| SCHEMBL8438483 | 0.78 | TSHR (0.60) | CYP2C9KDM4EMEN1CYP1A2CYP3A4 | |
| SCHEMBL7281077 | 0.77 | CACNA1F (0.53) | PYGLPYGMCYP2C9KDM4ECYP1A2 | |
| SCHEMBL7281634 | 0.77 | TSHR (0.42) | PYGLPYGMKDM4EHSD17B10TSHR | |
| SCHEMBL10765397 | 0.75 | CYP2C9 (0.52) | PYGLPYGMCYP2C9KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169009-A2 | Novel dihydropyridine derivatives and their production, formulation and use as pharmaceuticals | FISONS plc (GB) | 1986-01-22 | — | — | EP | claimed |
| EP-0169009-A2 | Novel dihydropyridine derivatives and their production, formulation and use as pharmaceuticals | FISONS plc (GB) | 1986-01-22 | — | — | EP | disclosed |