Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 16/20 | 0.52 |
| ▸ | PYGL | P06737 | 15/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9133557 | 0.80 | CYP2C9 (0.50) | PYGMPYGLLMNACYP2C9KDM4E | |
| SCHEMBL7275567 | 0.79 | PYGL (0.49) | PYGMPYGLLMNACYP2C9KDM4E | |
| SCHEMBL7945527 | 0.77 | LMNA (0.47) | PYGMPYGLLMNAL3MBTL1CYP2C9 | |
| SCHEMBL4881545 | 0.76 | LMNA (0.61) | PYGMPYGLLMNAL3MBTL1CYP2C9 | |
| SCHEMBL29664498 | 0.74 | CYP2C9 (0.60) | PYGMPYGLLMNACYP2C9KDM4E | |
| SCHEMBL7273889 | 0.74 | CYP2C9 (0.60) | PYGMPYGLLMNACYP2C9KDM4E | |
| Lemildipine SCHEMBL49443 | 0.74 | CYP2C9 (0.62) | PYGMPYGLLMNACYP2C9KDM4E | |
| Lemildipine SCHEMBL49442 | 0.74 | CYP2C9 (0.62) | PYGMPYGLLMNACYP2C9KDM4E | |
| Lemildipine SCHEMBL29801339 | 0.74 | CYP2C9 (0.62) | PYGMPYGLLMNACYP2C9KDM4E | |
| SCHEMBL28489460 | 0.72 | PYGM (0.59) | PYGMPYGLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028433-A | Vasodilators, Circulatory Diseases, Hypotensive Agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |