Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276148 | 0.81 | CYP3A4 (0.37) | DRD2MYCNR4A1CYP3A4NOTUM | |
| SCHEMBL7270171 | 0.79 | HTR3A (0.57) | — | |
| SCHEMBL9485099 | 0.71 | NOTUM (0.38) | KMT2AMYCNOTUM | |
| SCHEMBL9488302 | 0.71 | DRD2 (0.40) | DRD2MAPTNOTUM | |
| SCHEMBL7274861 | 0.70 | DRD2 (0.51) | DRD2MYCNR4A1CYP3A4NOTUM | |
| Hydrochloric Acid SCHEMBL7270776 | 0.69 | DRD2 (0.50) | DRD2MYCNR4A1CYP3A4NOTUM | |
| SCHEMBL9485028 | 0.68 | FFAR4 (0.36) | DRD2MYCNR4A1 | |
| SCHEMBL7279814 | 0.68 | LMNA (0.41) | MYCNR4A1CYP3A4NOTUM | |
| SCHEMBL7270772 | 0.68 | CYP3A4 (0.37) | DRD2MYCNR4A1CYP3A4NOTUM | |
| SCHEMBL7278134 | 0.68 | AKR1B1 (0.38) | DRD2MYCNR4A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407137-B1 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5185333-A | Dopamine D2 receptor blocking agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| EP-0407137-A2 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |