Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29482199 | 0.86 | CNR1 (0.58) | GAASMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL7121916 | 0.84 | SMN1; SMN2 (0.77) | GAASMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL7837591 | 0.81 | RXFP1 (0.62) | ALDH1A1TSHRHTTKMT2AMEN1 | |
| (2-Aminophenyl)(Morpholino)Methanone SCHEMBL30988542 | 0.80 | GAA (0.62) | GAASMN1; SMN2ALDH1A1TSHRHTT | |
| (2-Aminophenyl)(Morpholino)Methanone SCHEMBL11446442 | 0.80 | GAA (0.62) | GAASMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL554704 | 0.78 | MGLL (0.67) | GAASMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL20267430 | 0.78 | GAA (0.73) | GAASMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL11319556 | 0.77 | SMN1; SMN2 (0.62) | GAASMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL8396438 | 0.77 | GAA (0.62) | GAASMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL1663182 | 0.77 | ALDH1A1 (0.67) | GAASMN1; SMN2ALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541960-A2 | METHODS AND DEVICES FOR DETECTING HEPATITIS C VIRUS | Quest Diagnostics Investments LLC (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2017122174-A1 | DIFFERENTIAL SCANNING MICROCALORIMETER DEVICE FOR DETECTING DISEASE AND MONITORING THERAPEUTIC EFFICACY | MONASELIDZE JAMLET (GE) | 2017-07-20 | — | — | WO | disclosed |
| US-6265381-B1 | MORPHOLINOUREA AND RELATED DERIVATIVES OF PENTAFLUOROETHYL PEPTIDES | MERRELL PHARMACEUTICALS, INC. | 2001-07-24 | — | — | US | disclosed |
| US-5714470-A | PENTAFLUORO ALKYL TERMINATED PEPTIDE DERIVATIVES; TREATMENT OF INFLAMMATORY DISEASES, EMPHYSEMA AND CHRONIC BRONCHITIS | MERRELL PHARMACEUTICALS, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0529568-B1 | Novel orally-active elastase inhibitors | MERRELL PHARMA INC (US) | 1997-01-15 | — | — | EP | disclosed |
| US-5478811-A | Antiinflammatory agents, enzyme inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0529568-A1 | Novel orally-active elastase inhibitors | MERRELL PHARMACEUTICALS INC. (US) | 1993-03-03 | — | — | EP | disclosed |