Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272882 | 1.00 | HRH3 (0.48) | HRH3POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL7286910 | 0.89 | PKM (0.53) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7274839 | 0.89 | PKM (0.53) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7265280 | 0.89 | F2 (0.53) | HRH3POLBALDH1A1F2 | |
| SCHEMBL8633510 | 0.89 | F2 (0.53) | HRH3POLBALDH1A1F2 | |
| SCHEMBL7265335 | 0.80 | P2RX7 (0.50) | POLBMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1804892 | 0.77 | LMNA (0.55) | HRH3POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1237539 | 0.77 | LMNA (0.55) | HRH3POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL7266824 | 0.76 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1CASP1HSD17B10 | |
| SCHEMBL7282828 | 0.73 | F2 (0.56) | POLBMEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268190-B1 | PROLINAL DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | claimed |