Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.47 |
| ▸ | F2 | P00734 | 7/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.40 |
| ▸ | PROC | P04070 | 2/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276363 | 0.92 | F10 (0.42) | ITGB3ITGA2BF2F10ITGAV | |
| Hydrochloric Acid SCHEMBL7283577 | 0.91 | ITGB3 (0.41) | ITGB3ITGA2BF2F10PLG | |
| SCHEMBL7276721 | 0.90 | TRPV1 (0.43) | F2F10PLGKLKB1PROC | |
| SCHEMBL7274533 | 0.89 | TSHR (0.40) | ITGB3ITGA2BF2 | |
| Hydrochloric Acid SCHEMBL7289827 | 0.88 | ALDH1A1 (0.39) | — | |
| SCHEMBL7274469 | 0.88 | LMNA (0.42) | ITGB3ITGA2BF2 | |
| SCHEMBL7282210 | 0.87 | SIGMAR1 (0.44) | — | |
| SCHEMBL7284310 | 0.87 | NAMPT (0.41) | ITGB3ITGA2BF2 | |
| SCHEMBL7272690 | 0.87 | NAMPT (0.41) | ITGB3ITGA2BF2 | |
| SCHEMBL7272971 | 0.87 | NAMPT (0.41) | ITGB3ITGA2BF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |