Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274427 | 0.92 | ITGB3 (0.35) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7276603 | 0.81 | TBXA2R (0.35) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7282203 | 0.81 | SIGMAR1 (0.43) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7275947 | 0.80 | ALDH1A1 (0.37) | ALDH1A1TSHRSMN1; SMN2SIGMAR1MDM2 | |
| SCHEMBL7283910 | 0.80 | SIGMAR1 (0.40) | ALDH1A1TSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL7274653 | 0.79 | ITGB3 (0.40) | ITGB3ITGA2BALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7281748 | 0.79 | SIGMAR1 (0.40) | ALDH1A1TSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL7272947 | 0.79 | SIGMAR1 (0.40) | ALDH1A1TSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL7281938 | 0.79 | SIGMAR1 (0.40) | ALDH1A1TSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL7280204 | 0.78 | SIGMAR1 (0.39) | ALDH1A1TSHRSMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |