Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91352 | 0.84 | MEN1 (0.58) | MMP3CA12CA2CA9CYP19A1 | |
| SCHEMBL5028631 | 0.81 | ALOX15 (0.62) | MEN1KMT2AALOX15ESR1ESR2 | |
| SCHEMBL30268624 | 0.81 | ALOX15 (0.62) | MEN1KMT2AALOX15ESR1ESR2 | |
| SCHEMBL5848625 | 0.78 | MEN1 (0.47) | CA12CA2CA9CYP19A1MEN1 | |
| SCHEMBL5705421 | 0.78 | MEN1 (0.47) | CA12CA2CA9CYP19A1MEN1 | |
| SCHEMBL9622875 | 0.77 | ALOX5 (0.62) | MEN1KMT2AALOX15ESR1ESR2 | |
| SCHEMBL3339161 | 0.77 | ALOX15 (0.65) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL2786052 | 0.77 | KIF11 (0.59) | MMP3CA12CA2CA9CYP19A1 | |
| SCHEMBL15234719 | 0.77 | KIF11 (0.54) | MMP3CA12CA2CA9CA1 | |
| SCHEMBL31603805 | 0.77 | MMP3 (0.45) | MMP3CA12CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5677466-A | TESTING USING A AMIDINOPHENYL CONTAINING COMPOUND | DR. KARL THOMAE, GMBH (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0567967-B1 | Tritium-labelled fibrinogen-receptor-antagonists, their use and their production | THOMAE GMBH DR K (DE) | 1996-07-10 | — | — | EP | disclosed |
| EP-0567967-A1 | Tritium-labelled fibrinogen-receptor-antagonists, their use and their production | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |