Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR5 | P32302 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR5A | P47898 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345353 | 0.88 | ADRA2A (0.47) | CXCR5NPC1RAB9AHTR5APOLA1 | |
| SCHEMBL16836163 | 0.82 | CXCR5 (0.51) | CXCR5NPC1RAB9AMETAP1POLA1 | |
| SCHEMBL29346208 | 0.81 | CXCR5 (0.33) | CXCR5HSD17B10KDM4EALDH1A1MAPK1 | |
| SCHEMBL3309532 | 0.81 | ALDH1A1 (0.41) | CXCR5NPC1RAB9AHTR5AHSD17B10 | |
| SCHEMBL26402689 | 0.79 | ADRA2A (0.40) | CXCR5RAB9AHTR5APOLA1HSD17B10 | |
| Hydrochloric Acid SCHEMBL31435767 | 0.79 | ADRA2A (0.40) | CXCR5RAB9AHTR5APOLA1HSD17B10 | |
| Hydrochloric Acid SCHEMBL26127895 | 0.79 | ADRA2A (0.40) | CXCR5RAB9AHTR5APOLA1HSD17B10 | |
| SCHEMBL3307587 | 0.78 | SMN1; SMN2 (0.52) | CXCR5NPC1RAB9AHTR5AHSD17B10 | |
| SCHEMBL7277003 | 0.78 | HSD17B1 (0.42) | MAOBKDM4EALDH1A1CYP3A4 | |
| SCHEMBL23811628 | 0.78 | DRD2 (0.45) | HTR5AMETAP1POLA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |