Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | NAMPT | P43490 | 7/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285483 | 0.94 | NR1H2 (0.41) | KDM4EPKMITGB3ITGA2BNAMPT | |
| SCHEMBL7276445 | 0.94 | NAMPT (0.40) | KDM4EPKMNAMPTOPRM1SIGMAR1 | |
| SCHEMBL7286536 | 0.93 | ITGB3 (0.43) | KDM4EPKMITGB3ITGA2BNAMPT | |
| SCHEMBL7286501 | 0.92 | KDM4E (0.43) | KDM4EPKMITGB3ITGA2BSIGMAR1 | |
| SCHEMBL7283192 | 0.89 | NR1H2 (0.40) | KDM4EPKMNAMPTOPRM1SIGMAR1 | |
| SCHEMBL7285724 | 0.87 | ITGB3 (0.41) | KDM4EPKMITGB3ITGA2BNAMPT | |
| SCHEMBL7286655 | 0.87 | NAMPT (0.42) | KDM4EPKMITGB3ITGA2BNAMPT | |
| SCHEMBL7284329 | 0.87 | ACACB (0.41) | KDM4EPKMITGB3ITGA2BOPRM1 | |
| SCHEMBL7271758 | 0.87 | SIGMAR1 (0.38) | ITGB3ITGA2BOPRM1SIGMAR1HTR1A | |
| SCHEMBL7283983 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BNAMPTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | disclosed |
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |